Journal Article by VFIC Researchers Ranked in Top 10 Most Read

Journal article, 5-Geranyloxy-7-Methoxycoumarin Inhibits Colon Cancer (SW480) Cells Growth by Inducing Apoptosis, ranked number eight in a list of the top 10 most popular articles in Planta Medica for the months of January-April. Authors of this article are as follows: Jaiprakash R. Patil, Guddadarangavvanahally K. Jayaprakasha, Jinhee Kim, Kotamballi N. Chidambara Murthy, Mahadev B. Chetti, Sang-Yong Nam, and Bhimanagouda S. Patil.

Abstract:
For the first time, three coumarins were isolated from the hexane extract of limes (Citrus aurantifolia) and purified by flash chromatography. The structures were identified by NMR (1D, 2D) and mass spectral analyses as 5-geranyloxy-7-methoxycoumarin, limettin, and isopimpinellin. These compounds inhibited human colon cancer (SW-480) cell proliferation, with 5-geranyloxy-7-methoxycoumarin showing the highest inhibition activity (67 %) at 25 µM. Suppression of SW480 cell proliferation by 5-geranyloxy-7-methoxycoumarin was associated with induction of apoptosis, as evidenced by annexin V staining and DNA fragmentation. In addition, 5-geranyloxy-7-methoxycoumarin arrested cells at the G0/G1 phase, and induction of apoptosis was demonstrated through the activation of tumour suppressor gene p53, caspase8/3, regulation of Bcl2, and inhibition of p38 MAPK phosphorylation. These findings suggest that 5-geranyloxy-7-methoxycoumarin has potential as a cancer preventive agent.

 

A PDF link of the whole article can be accessed by clicking on the following link: 5-Geranyloxy-7-Methoxycoumarin Inhibits Colon Cancer (SW480) Cells Growth by Inducing Apoptosis

 

Aggie From Brazil Named Outstanding International Alumnus

Dr. José Geraldo Eugênio de França was a post-doc researcher at the VFIC in 1997. We are proud of his accomplishments and congratulate him for receiving this prestigious award!

Dr. José Geraldo Eugênio de França

Dr. José Geraldo Eugênio de França, Class of 1990, has been named the recipient of Texas A&M University’s 2013 Outstanding International Alumnus Award.

Director of Research and Graduate Studies at the Technological Institute of Pernambuco, in Recife, Brazil, Eugênio, was presented the award Tuesday (April 9) by Texas A&M President R. Bowen Loftin and The Association of Former Students’ President and CEO Porter S. Garner III, along with David Heath, chair of the association’s board, and Vice Chancellor and Dean Mark A. Hussey of the College of Agriculture and Life Sciences.

Eugênio leads a group working to upgrade the research and innovation capabilities of the local industry and the engineering teaching capacity of the universities and private schools. He is also committed to better understanding the bioenergy and biofuels industry in Brazil and in the USA.

“Texas A&M University was such a turning point in my life – it made me committed to this great university forever,” said Eugênio. “I would like to share this moment with my family, teachers, professors, colleagues and friends who I had the grace to meet during this amazing journey.”

“Dr. Eugênio adheres to the values that we seek to instill in our students, most notably loyalty, selfless service and leadership,” said President Loftin. “He has touched many lives in his country and created long lasting collaborations with Texas A&M University. We are very proud to have him represent Texas A&M in Brazil as our Outstanding International Alumnus.”

Born in the Federative Republic of Brazil, Eugênio earned his bachelor’s degree in agriculture from Federal Rural University in Brazil (1978), his master’s degree in plant breeding from Andhra Pradesh Agricultural University in India (1983), now known as the Acharya N. G. Ranga Agricultural University and International Crops Research Institute for the Semi-Arid Tropics, and a Ph.D. in soil and crop science (1990) from Texas A&M.

“The Outstanding International Alumnus Award exists to formally acknowledge those unique former students who came to Texas A&M from across national and cultural boundaries and who now serve as loyal ambassadors of the worldwide Aggie Network,” said Garner. “Dr.  Eugênio is truly deserving of this prestigious award as he embodies the Spirit of Aggieland and reflects it in ways that make us all proud.”

“Recognizing Dr. Eugênio for his exceptional work is a great pleasure for me,” said Vice Chancellor and Dean of the College of Agriculture and Life Sciences Mark A. Hussey. “As a land-grant university with a mission of promoting education, research, service and extension, we know that not only is his work an admirable example of that mission, it also represents our dedication to expand our reach worldwide.”

His 25- year career has taken Eugênio from northeastern region of Brazil, where he was a cereal or sorghum and vegetable breeder, to the halls of academia. He has moved from teaching biology at a local college in Vitoria de Santo Antao to serving as president of the Agriculture Research Institute to secretary of Agriculture in the State of Pernambuco in 1995, before moving on to service in the Ministry of Agriculture in 1996.

 

You can view the rest of the story by clicking on the following link: TAMU Times.

Artichokes finding a place in the ‘heart’ of Texas

Nutrition research shows that in addition to being an excellent source of dietary fiber, artichokes contain high levels of antioxidants and potassium. They are a staple of the Mediterranean diet, noted for its health benefits. Photo By: Texas A&M ArgiLife Research

Nutrition research shows that in addition to being an excellent source of dietary fiber, artichokes contain high levels of antioxidants and potassium. They are a staple of the Mediterranean diet, noted for its health benefits.
Photo By: Texas A&M ArgiLife Research

By: Paul Schattenberg

BROWNSVILLE — It was cool and overcast during the recent harvest of a 12-acre field of artichokes being grown by MO Produce LLC in Rancho Viejo, near Brownsville.

As the workers methodically harvested the fist-size globes from the tops of plants, Mike Ortiz, one of the operation’s owners, oversaw the harvest and inspected the rest of the crop.

A worker harvests artichokes  grown by MO Produce LLC in Rancho Viejo. The grower has been successfully producing artichokes in the Rio Grande Valley for the past five years.
(Texas A&M AgriLife Extension Service photo)

“This is our fifth year for growing artichokes here in the Rio Grande Valley and we’ve had good success with them so far, especially with help from the Texas A&M Research and Extension Center in Uvalde,” said Ortiz, who has a bachelor’s degree in agricultural development from Texas A&M University.

While more than 95 percent of U.S. artichoke production is currently in California, Ortiz and his business partner, Jed Murray, himself a California ‘transplant’ to the Lower Rio Grande Valley, have been giving the artichoke a home where the armadillo and roadrunner roam.

“There is currently some fledgling commercial production in the Rio Grande Valley and Winter Garden area, with additional small-scale production in the Hill Country and in the Austin and Dallas area,” said Dr. Daniel Leskovar, Texas A&M AgriLife Research vegetable physiologist and Uvalde center director. “There are also many home gardeners throughout the state who grow artichokes in small veggie garden plots. But the artichoke as a commercial crop is still a relative newcomer to Texas.”

Since 2007, Ortiz and Murray have been consulting with Leskovar on various aspects of artichoke production. He and his fellow researchers have provided them research-based information and assistance on variety selection, transplantation, irrigation and various production methods so they might produce artichokes that will meet or exceed consumer expectations.

“From a production standpoint, artichokes are a reasonably low-maintenance crop,” Ortiz said. “In general, they require about the same amount of effort as say cabbage or onions. Plus, they have a much better profit potential than most of the traditional crops produced in the Valley.”

Murray, who also is president of the Texas Vegetable Association headquartered in nearby Mission, said customer feedback proves the operation is headed in the right direction.

“Our customers tell us they like the freshness, the nutty flavor and the big heart of the artichokes we grow here,” Murray said. “We frequently get compliments and expressions of gratitude from them.”

Murray said part of their marketing strategy is to introduce artichokes to audiences that don’t have a tradition of using them as ingredients in their recipes and to alert them to their many healthful qualities.

“Once they get a taste and realize how good they are, plus realize their exceptional nutritional value, they’ll want to add them to their weekly shopping list,” he said.

Both Murray and Ortiz practice what they preach, frequently cooking artichokes for their own families, which include a total of seven children.

“We make cooking artichokes a kind of family activity at my house,” Ortiz said. “I’ll parboil  them in a little water and oil, plus some salt and a few spices, then put them on the grill. The kids actually fight over who gets served first.”

Otriz added that his 97-year-old Spanish grandfather who lives nearby grew up in the tradition of eating artichokes as a part of his normal diet.

“I guess you could say he’s living proof they’re good for you,” Ortiz said jokingly.

It’s not just Rio Grande Valley-area consumers who are delighted with their artichokes, Murray said. MO Produce can now count Whole Foods, as well as another Texas-based supermarket chain, among its artichoke fan — and customer – base.

“We’re excited that we can produce a fresh, flavorful, local product that is both healthy and nutritious,” Murray said. “We also strive to leave a small carbon footprint from our production and transportation.”

Artichokes are a key food in the Mediterranean diet, which has been scientifically proven to have exceptional health benefits, said Dr. Sharon Robinson, Texas A&M AgriLife Extension Service nutrition specialist in College Station.

“They are high in dietary fiber and low in calories, plus they’re rich in antioxidants and potassium,” Robinson said.

 She noted that a recently completed 5-year study in Spain showed participants with heart-risk health issues following a Mediterranean-type diet had a 30 percent lower combined rate of heart attack, stroke and death from related causes than those following a typical low-fat diet.

Celebrity chef Jesse Griffiths, owner of Dai Due Butcher Shop and Supper Club in Austin, is another fan of artichokes, especially Texas artichokes. According to the Austin Food and Wine Alliance, Griffiths uses locally-grown vegetables, meats and dairy products in his recipes, focusing on “traditional, local and sustainable foods.”

“I’ve been buying artichokes from Mike and Jed for three or four years now and they have always been very high quality,” Griffiths said. “I would describe them as sweet with a nut-like or slightly ‘woody’ taste and excellent texture. I enjoy using them in my dishes and look forward to the times when they’re available to me.”

Murray said while most of their business outside the Rio Grande Valley currently comes from the Austin area, they are hoping to also break into the San Antonio, Houston and Dallas markets. They are also assessing the possibility of organic artichoke production.

“Our research on artichoke production, which began in 2005 at the Uvalde center and in conjunction with the Food for Health Program, has shown the artichoke to be a viable alternative crop for many areas of the state,” Leskovar said. “We have studied crop yield, quality and nutritional aspects of several different varieties of artichoke in relation to different irrigation regimes and nitrogen fertilization rates. We also focused on water-use rates as this region is water-limited and prone to drought, as well as on the heat tolerance of artichoke varieties.”

Leskovar said center research is also investigating how to extend the spring growing season so operations can take advantage of the higher off-season prices.

In Texas, he said, artichokes are grown as annuals or possibly bi-annuals where re-sprouting is possible. Seedlings are raised in greenhouses in South Texas, and are transplanted into the field during the fall and harvested in the spring. There is also a niche market for the flower produced by the artichoke plant.

“Development of year-round management strategies focused on producing artichoke heads in the spring and fall in areas of the state will give producers with a positive market opportunity to sell their product at the best possible price.

“There’s a lot of additional potential for artichoke production in other regions of Texas, but it will take additional research, as well as the necessary funding to support that research and various practical aspects of production, to realize that potential.”

Leskovar said the nutritional value to the consumer and profit potential to the producer make the artichoke a stand-out alternative crop for many parts of the state. And soon, Leskovar and AgriLife Extension agricultural economist Dr. Marco Palma, College Station, will conduct a consumer preference study using fresh-market artichokes from MO Produce in comparison with other fresh-market and processed artichokes.

“We are continuing our artichoke research at the Uvalde center with partial funding from the Texas Department of Agriculture. Early indications of new field variety trials are showing  good commercial potential for early and late variety selections with  traditional green heads and also red to maroon color heads,” he said. “These too may provide some more interesting opportunities for Texas producers.”

Leskovar cited the success of MO Produce in artichoke production as an excellent example of how research-based knowledge and technical assistance can be applied to practical agricultural production to benefit both the producer and consumer.

Professor Studies Plants, Foods to Prevent Cancer

Photo by: Tom Reel / San Antonio Express-News Michael Wargovich, a professor of molecular medicine at the University of Texas Health Science Center, displays a small bag of mixed plant life remedies as he talks about his research on foods that inhibit cancer. Wargovich is studying foods with anti-inflammatory properties, including fruits, vegetables, spices and herbs.

Photo by: Tom Reel / San Antonio Express-News
Michael Wargovich, a professor of molecular medicine at the University of Texas Health Science Center, displays a small bag of mixed plant life remedies as he talks about his research on foods that inhibit cancer. Wargovich is studying foods with anti-inflammatory properties, including fruits, vegetables, spices and herbs.

Story by Jennifer R. Lloyd, San Antonio Express-News

Twigs, leaves and berries may sound like the diet of the destitute, but for molecular medicine professor Michael Wargovich, certain plants — like those in traditional medicines and food in developing countries — could be gold mines in the fight against cancer.

In his newly outfitted lab at the University of Texas Health Science Center at San Antonio, Wargovich and his staff are testing the cancer-preventing properties of green tea. They’ll also soon start investigating the anti-inflammatory abilities of the neem tree, native to India , and which already is used in some toothpastes available in the United States.

Wargovich, 60, cited World Health Organization statistics showing that the hot spots for cancer will move south of the equator by 2020 as the population swells and its residents, immunized from many infectious diseases, live longer and assume a more Western lifestyle.

To read the rest of the story, click on the following link: http://www.mysanantonio.com/news/education/article/Professor-studies-plants-foods-to-prevent-cancer-4362239.php#ixzz2PJV3TTkV

The Packer Names Importer of the Year

Bassetti_Packer_import_award

With its Importer of the Year award, The Packer recognizes Jimmy Bassetti (left), president of J&D Produce, Edinburg, Texas, shown with his son, James, a production assistant at the company. Bassetti received the award March 7 during the America Trades Produce conference in McAllen, Texas.
Photo by Fred Wilkinson, The Packer

McALLEN, Texas — Jimmy Bassetti, founder and owner of J&D Produce Inc., Edinburg, receivedThe Packer’s 2013 Importer of the Year Award March 7 at the America Trades Produce conference.

“He has a really broad perspective about the industry,” said Bret Erickson, president of Mission-based Texas International Produce Association, which co-sponsors the event in cooperation with the Fresh Produce Association of the Americas, Nogales, Ariz.

To see the rest of this story, click the following link: The Packer names Importer of the Year

For further information, visit www.thepacker.com

Eating Fruits and Vegetables Makes You Calmer, Happier, More Energetic

fruits & vegetables

 

By: ISHS Secretariat

Study suggests many apples a day keep the blues at bay.

Eating more fruit and vegetables may make young people calmer, happier and more energetic in their daily life, new research from the University of Otago (New Zealand) suggests.

Department of Psychology researcher Dr Tamlin Conner, and Dr Caroline Horwath and Bonnie White from Otago’s Department of Human Nutrition, investigated the relationship between day-to-day emotions and food consumption.

The study is published in the British Journal of Health Psychology, Thursday, 24 January 2013.

A total of 281 young adults (with a mean age of 20 years) completed an internet-based daily food diary for 21 consecutive days. Prior to this, participants completed a questionnaire giving details of their age, gender, ethnicity, weight and height. Those with a history of an eating disorder were excluded.

On each of the 21 days participants logged into their diary each evening and rated how they felt using nine positive and nine negative adjectives. They were also asked five questions about what they had eaten that day. Specifically, participants were asked to report the number of servings eaten of fruit (excluding fruit juice and dried fruit), vegetables (excluding juices), and several categories of unhealthy foods like biscuits/cookies, potato crisps, and cakes/muffins.

The results showed a strong day-to-day relationship between more positive mood and higher fruit and vegetable consumption, but not other foods.

“On days when people ate more fruits and vegetables, they reported feeling calmer, happier and more energetic than they normally did,” says Dr Conner.

To understand which comes first – feeling positive or eating healthier foods – Dr Conner and her team ran additional analyses and found that eating fruits and vegetables predicted improvements in positive mood the next day, suggesting that healthy foods may improve mood. These findings held regardless of the BMI of individuals.

“After further analysis we demonstrated that young people would need to consume approximately seven to eight total servings of fruits and vegetables per day to notice a meaningful positive change. One serving of fruit or vegetables is approximately the size that could fit in your palm, or half a cup. My co-author Bonnie White suggests that this can be done by making half your plate at each meal vegetables and snacking on whole fruit like apples,” says Dr Conner.

She adds that while this research shows a promising connection between healthy foods and healthy moods, further research is necessary and the authors recommend the development of randomised control trials evaluating the influence of high fruit and vegetable intake on mood and well being.

For more information, contact: Dr Tamlin Conner, Department of Psychology, University of Otago, New Zealand. Tel +64 3 479 7624; Mob +64 21 984 332; Emailtconner@psy.otago.ac.nz

To see the original article, click the following link: ISHS News

White Delight: New Peach Varieties Released for Warmer Climates

Peach Blossom

Peach tree blossoms in the research plots of Dr. David Byrne in College Station, Texas. (Texas A&M AgriLife Research photo by Kathleen Phillips)

 

By: Kathleen Phillips

COLLEGE STATION – Southerners who have been anxiously awaiting a peach tree that will produce in warmer climates – just chill.

Four new varieties being released for production in nurseries this year will soon be available for growers where cold temperatures – a necessity for peach trees – are less likely, according to Texas A&M AgriLife Research stone fruit breeder Dr. David Byrne.

“This is a first,” Byrne said. “These are unique because there are few low-acid white peaches available to be grown in our adaptation zone.”

Most white flesh peaches found in the produce section in grocery stores are grown in California, he said. White fleshed peaches are preferred in China, Japan Taiwan, and white fleshed peaches were initially planted in California to supply those markets.

According to the California Fruit Tree Agreement statistics, white fleshed peaches began to appear as a niche product in the U.S. market by 2000 and are now commonly found in grocery stores throughout the season.

           “The four varieties — called White Delight series — are named for their excellent flavor and  color of their flesh, which ranges from creamy white to as much as 80 percent striped red or orange-red,” Byrne said.

Three of the new varieties are clingstone while one is semi-freestone, and they ripen consecutively from late-May through mid-July, Byrne noted.

           The seed for these new crosses were originally planted in 1998 and had shown consistent production in three locations – Fairfield and College Station, Texas, and Fresno, Calif. – since 2006. Fruit from the research trees scored high in taste tests, Byrne said.

Nurseries can obtain budwood under a license agreement with AgriLife Research.

 

 

Farmers Markets Driving Tomato Research

Dr. Raul Villanueva

Dr. Raul Villanueva, an entomologist at the Texas A&M AgriLife Research and Extension Center at Weslaco, conducts research on tomatoes to reduce damage from insects and viruses. (AgriLife Communications photo by Rod Santa Ana)

By: Rod Santa Ana

WESLACO  –  The emergence of farmers markets in the Lower Rio Grande Valley has led to new research that shows planting dates affect the productivity of organic tomatoes, according to an expert at the Texas A&M AgriLife Research and Extension Center at Weslaco.

“Just a few years ago, between Brownsville and Rio Grande City, there were no farmers markets anywhere,” said Dr. Raul Villanueva, an AgriLife Extension entomologist.

“Now, there are seven or eight that are all doing very well. The demand for fresh, locally grown fruits and vegetables is obviously high and growing, especially for organic produce.”

But growing fruits and vegetables in the subtropical climate of South Texas without the use of synthetic insecticides is a real challenge, especially when it comes to tomatoes, Villanueva said.

“People who grow produce for farmers markets here have become quite successful in going organic, but they were really having problems with tomatoes,” he said. “That’s due to a virus spread by whiteflies that severely limits production. It’s called yellow leaf curl virus.

“In fact, that virus, coupled with competition from Mexico, is why tomatoes are not grown here commercially like they were back in the 1950s and 60s. There are some tomatoes still grown here for canning, but the acreage is very small, about 200 acres.”

The virus debilitates the plant, causes plant leaves to curl upward along the edges and can knock tomato production to zero, Villanueva said. Whiteflies are abundant because they feed on other crops, including cotton, corn, watermelon and others, creating continuous populations that feed on and transmit viruses to tomatoes, watermelon and potatoes.

To help today’s producers, Villanueva planted tomato varieties he knew were especially susceptible to yellow leaf curl virus at various dates between Sept. 17 and Oct. 5.

“What we found was that those planted early were the most infected,” he said. “They had very low yields and some produced no fruit at all. Those planted on Oct. 5 had one and a half times the yield of those planted early and the rate of infection was low.”

Villanueva thinks later planting dates help tomatoes resist the virus because whitefly populations are lower then.

“So, our early recommendations are that growers change their planting dates. But we have lots more research to do because some of our findings were very likely affected by drought. We also need to evaluate newly developed tomato varieties that have tolerance or resistance to yellow leaf curl virus.”

Those additional varieties are being developed by Dr. Kevin Crosby, an associate professor and vegetable breeder in College Station once stationed at the AgriLife Research and Extension Center at Weslaco.

“Through collaborations with colleagues in Taiwan and Florida, we have successfully integrated multiple virus-resistance genes into our heat-tolerant tomato lines to create several promising experimental varieties,” Crosby said. “These include beefsteak, saladette and heirloom type fruits on determinate plants.”

Determinate plants are relatively compact plants on which all the fruit sets and matures at the same time.

Villanueva said improved tomato varieties coupled with optimal planting dates could promote increased production as well as a healthier lifestyle here.

“All of this research and information is important to the future success of farmers markets,” Villanueva said. “And farmers markets are important because they improve the lives of both growers and consumers here. Growers become economically self-sufficient, and consumers enjoy the healthy benefits of organic produce.”

Villanueva said he worked closely with growers in the Harlingen and Weslaco areas who are considered transition growers, small acreage producers who are trying to wean their production from the use of organic insecticides and become fully organic.

For more information, contact: Writer: Rod Santa Ana, 956-878-8317, r-santaana@tamu.edu Contact: Raul Villanueva, 956-968-5581383-1026, rtvillanueva@ag.tamu.edu

Optimists Eat More Veggies

People who have high blood levels of healthy plant compounds, known as carotenoids, also tend to be more optimistic about the future, a new study has found.

Links between psychological health and physical health have long been recognized by researchers.

However, most research has focused on poor psychological functioning, such as how being depressed or anxious may be bad for health, according to lead study author Julia Boehm, a research fellow at the Harvard School of Public Health.

To read more of this article by Lindsey Konkel in Live Science, click the link below.

Optimists Eat More Veggies

Scientist Spotlight

 

Dr. Jay Spotlight

If you are interested in reading the full papers for Dr. Jayaprakasha’s featured articles, the links can be found below.

Studies on the Antioxidant Activity of Pomegranate (Punica granatum) Peel and Seed Extracts Using in Vitro Models

Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro

Inhibition of Prostate Cancer (LNCaP) Cell Proliferation by Volatile Components from Nagami Kumquats